GETEROHALQALI BIRIKMALAR ASOSIDA ISHLAB CHIQARILADIGAN ZAMONAVIY DORI VOSITALARI.
Abstract
Maqola geterohalqali birikmalarning farmatsevtikada qo‘llanilishi va ular asosida yaratilgan zamonaviy dori vositalarining ahamiyatiga bag‘ishlangan. Azot, kislorod va oltingugurt kabi geteroatomlarni o‘z ichiga olgan birikmalarning biologik faolligi va selektivligi ularning dorivor preparatlar yaratishdagi muhim xususiyatlari sifatida ko‘rsatilgan. Pirimidin, purin, imidazol, kumarin, furan, tiazolidin kabi geterotsiklik birikmalardan antibakterial, yallig‘lanishga qarshi, saraton va diabetga qarshi samarali dorilar tayyorlanishi tahlil qilingan. Shuningdek, beta-laktamli antibiotiklar, qo‘ziqorinlarga qarshi preparatlar va qon ivishini kamaytiruvchi dori vositalarining ishlab chiqarilishida ushbu birikmalar muhim ahamiyatga ega ekanligi ko‘rsatilgan. Hozirgi vaqtda geterohalqali birikmalar asosida biologik faol dori vositalarini ishlab chiqish va rivojlantirish farmatsevtika sanoatining dolzarb yo‘nalishi hisoblanadi. Mazkur tadqiqotlar yangi dorilar yaratish orqali murakkab kasalliklarni davolashda zamonaviy tibbiyotga salmoqli hissa qo‘shmoqda.
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