DETECTION OF SYSTEMIC LUPUS ERYTHEMATOSUS: INNOVATIVE DIAGNOSTIC METHODS
Keywords:
systemic lupus erythematosus, autoimmune disease, diagnosis, serological markers, imaging, genetic testingAbstract
Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease characterized by multisystem involvement and a wide range of clinical manifestations. Early and accurate diagnosis of SLE is crucial for effective management and prevention of complications. Over the years, significant advancements have been made in diagnostic techniques, including serological markers, imaging modalities, and genetic testing. This article explores the modern diagnostic methods for SLE, focusing on their accuracy, accessibility, and clinical relevance.
References
1. Tsokos, G. C. (2011). Systemic lupus erythematosus. New England Journal of Medicine, 365(22), 2110-2121.
2. Petri, M., Orbai, A. M., Alarcón, G. S., Gordon, C., Merrill, J. T., Fortin, P. R., ... & Costenbader, K. H. (2019). Derivation and validation of the Systemic Lupus International Collaborating Clinics classification criteria for SLE. Arthritis & Rheumatology, 71(9), 1400-1412.
3. Aringer, M., Costenbader, K., Daikh, D., Brinks, R., Mosca, M., Ramsey-Goldman, R., ... & Johnson, S. R. (2019). 2019 European League Against Rheumatism/American College of Rheumatology classification criteria for systemic lupus erythematosus. Annals of the Rheumatic Diseases, 78(9), 1151-1159.
4. Pisetsky, D. S., & Lipsky, P. E. (2020). New insights into the role of antinuclear antibodies in systemic lupus erythematosus. Nature Reviews Rheumatology, 16(10), 565-579.
5. Wallace, D. J., & Hahn, B. H. (Eds.). (2019). Dubois' lupus erythematosus and related syndromes. Elsevier Health Sciences.
6. Bertsias, G., Ioannidis, J. P., Boletis, J., Bombardieri, S., Cervera, R., Dostal, C., ... & Boumpas, D. T. (2008). EULAR recommendations for the management of systemic lupus erythematosus with neuropsychiatric manifestations: report of a task force of the EULAR standing committee for clinical affairs. Annals of the Rheumatic Diseases, 67(5), 687-696.
7. Gatto, M., Zen, M., Iaccarino, L., & Doria, A. (2013). Emerging and critical issues in the pathogenesis of lupus. Autoimmunity Reviews, 12(4), 523-536.
8. Choi, J., & Kim, S. T. (2017). Biomarkers of systemic lupus erythematosus: cytokines, chemokines, and interferons. Clinical and Experimental Rheumatology, 35(4), 561-570.
